Toll-like-Rezeptor 2

Mikita N et al. (2009) No involvement of non-synonymous TLR2 polymorphisms in Japanese leprosy patients.

Shishido T et al. (2003) Toll-like receptor-2 modulates ventricular remodeling after myocardial infarction.

Ogus AC et al. (2004) The Arg753GLn polymorphism of the human toll-like receptor 2 gene in tuberculosis disease.

Bornstein SR et al. (2004) Impaired adrenal stress response in Toll-like receptor 2-deficient mice.

Hoebe K et al. (2005) CD36 is a sensor of diacylglycerides.

Malhotra D et al. (2005) TLR2 Arg677Trp polymorphism in leprosy: revisited.

Schröder NW et al. (2005) Heterozygous Arg753Gln polymorphism of human TLR-2 impairs immune activation by Borrelia burgdorferi and protects from late stage Lyme disease.

Mullick AE et al. (2005) Modulation of atherosclerosis in mice by Toll-like receptor 2.

Boraska Jelavić T et al. (2006) Microsatelite GT polymorphism in the toll-like receptor 2 is associated with colorectal cancer.

Sato A et al. (2006) Dual recognition of herpes simplex viruses by TLR2 and TLR9 in dendritic cells.

Schauber J et al. (2007) Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism.

Rolls A et al. (2007) Toll-like receptors modulate adult hippocampal neurogenesis.

Bochud PY et al. (2008) Toll-like receptor 2 (TLR2) polymorphisms are associated with reversal reaction in leprosy.

Darville T et al. (2003) Toll-like receptor-2, but not Toll-like receptor-4, is essential for development of oviduct pathology in chlamydial genital tract infection.

Kim S et al. (2009) Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis.

Alves-Filho JC et al. (2009) Regulation of chemokine receptor by Toll-like receptor 2 is critical to neutrophil migration and resistance to polymicrobial sepsis.

Manicassamy S et al. (2009) Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity.

Tanigawa K et al. (2009) Tryptophan aspartate-containing coat protein (CORO1A) suppresses Toll-like receptor signalling in Mycobacterium leprae infection.

Hise AG et al. (2009) An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans.

Almeida PE et al. (2009) Mycobacterium bovis bacillus Calmette-Guérin infection induces TLR2-dependent peroxisome proliferator-activated receptor gamma expression and activation: functions in inflammation, lipid metabolism, and pathogenesis.

West XZ et al. (2010) Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands.

Toubiana J et al. (2011) IMPDHII protein inhibits Toll-like receptor 2-mediated activation of NF-kappaB.

Round JL et al. (2011) The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota.

Xiong Y et al. (2012) R753Q polymorphism inhibits Toll-like receptor (TLR) 2 tyrosine phosphorylation, dimerization with TLR6, and recruitment of myeloid differentiation primary response protein 88.

Shirey KA et al. (2013) The TLR4 antagonist Eritoran protects mice from lethal influenza infection.

Spurthi KM et al. (2018) Toll-like receptor 2 deficiency hyperactivates the FoxO1 transcription factor and induces aging-associated cardiac dysfunction in mice.

Brightbill HD et al. (1999) Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors.

Rock FL et al. (1998) A family of human receptors structurally related to Drosophila Toll.

Muzio M et al. (2000) Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells.

Xu Y et al. (2000) Structural basis for signal transduction by the Toll/interleukin-1 receptor domains.

Takeuchi O et al. (2002) Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins.

Alexopoulou L et al. (2002) Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice.

Krutzik SR et al. (2003) Activation and regulation of Toll-like receptors 2 and 1 in human leprosy.

West AP et al. (2011) TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.

Takeuchi O et al. (2000) Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection.

Blander JM et al. (2004) Regulation of phagosome maturation by signals from toll-like receptors.

Jiang D et al. (2005) Regulation of lung injury and repair by Toll-like receptors and hyaluronan.

Zhang D et al. (2015) Neutrophil ageing is regulated by the microbiome.

Chaudhary PM et al. (1998) Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans.

Kadowaki N et al. (2001) Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens.

Aliprantis AO et al. (1999) Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2.

Hirschfeld M et al. (1999) Cutting edge: inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2.

Underhill DM et al. (1999) The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens.

Aderem A et al. (2000) Toll-like receptors in the induction of the innate immune response.

Harju K et al. (2001) Ontogeny of Toll-like receptors Tlr2 and Tlr4 in mice.

Thoma-Uszynski S et al. (2001) Induction of direct antimicrobial activity through mammalian toll-like receptors.

Kang TJ et al. (2001) Detection of Toll-like receptor 2 (TLR2) mutation in the lepromatous leprosy patients.

Re F et al. (2001) Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells.

Wolfs TG et al. (2002) In vivo expression of Toll-like receptor 2 and 4 by renal epithelial cells: IFN-gamma and TNF-alpha mediated up-regulation during inflammation.

Supajatura V et al. (2002) Differential responses of mast cell Toll-like receptors 2 and 4 in allergy and innate immunity.

Oliveira RB et al. (2003) Expression of Toll-like receptor 2 on human Schwann cells: a mechanism of nerve damage in leprosy.

Bochud PY et al. (2003) Cutting edge: a Toll-like receptor 2 polymorphism that is associated with lepromatous leprosy is unable to mediate mycobacterial signaling.