Klinisch | Untersuchungsmethoden | Familienuntersuchung |
Bearbeitungszeit | 5 Tage | |
Probentyp | genomische DNS |
Klinisch | Untersuchungsmethoden | Hochdurchsatz-Sequenzierung |
Bearbeitungszeit | 25 Tage | |
Probentyp | genomische DNS |
Klinisch | Untersuchungsmethoden | Direkte Sequenzierung der proteinkodierenden Bereiche eines Gens |
Bearbeitungszeit | 25 Tage | |
Probentyp | genomische DNS |
Klinisch | Untersuchungsmethoden | Multiplex ligationsabhängige Amplifikation |
Bearbeitungszeit | 25 Tage | |
Probentyp | genomische DNS |
1. |
Trask B et al. (1993) Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers. ![]() |
2. |
Paolini M et al. (1999) Co-carcinogenic effect of beta-carotene. ![]() |
3. |
Thum T et al. (2000) Gene expression in distinct regions of the heart. ![]() |
4. |
Tsuchiya K et al. (2004) Homozygous CYP2B6 *6 (Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenz-containing regimens. ![]() |
5. |
Haas DW et al. (2004) Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study. ![]() |
6. |
Cressey TR et al. (2007) Pharmacogenetics of antiretroviral drugs for the treatment of HIV-infected patients: an update. ![]() |
7. |
Blievernicht JK et al. (2007) MALDI-TOF mass spectrometry for multiplex genotyping of CYP2B6 single-nucleotide polymorphisms. ![]() |
8. |
Davaalkham J et al. (2009) Allele and genotype frequencies of cytochrome P450 2B6 gene in a Mongolian population. ![]() |
9. |
Watanabe T et al. (2010) Functional characterization of 26 CYP2B6 allelic variants (CYP2B6.2-CYP2B6.28, except CYP2B6.22). ![]() |
10. |
Carr DF et al. (2010) Haplotype structure of CYP2B6 and association with plasma efavirenz concentrations in a Chilean HIV cohort. ![]() |
11. |
Elens L et al. (2010) Influence of host genetic factors on efavirenz plasma and intracellular pharmacokinetics in HIV-1-infected patients. ![]() |
12. |
Radloff R et al. (2013) Novel CYP2B6 enzyme variants in a Rwandese population: functional characterization and assessment of in silico prediction tools. ![]() |
14. |
Miles JS et al. (1988) A novel human cytochrome P450 gene (P450IIB): chromosomal localization and evidence for alternative splicing. ![]() |
15. |
Santisteban I et al. (1988) The major phenobarbital-inducible cytochrome P-450 gene subfamily (P450IIB) mapped to the long arm of human chromosome 19. ![]() |
16. |
Mizukami Y et al. (1983) Gene structure of a phenobarbital-inducible cytochrome P-450 in rat liver. ![]() |