Toll-like receptor 9

Imaeda AB et al. (2009) Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome.

Honda K et al. (2005) Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction.

Cunningham-Rundles C et al. (2006) TLR9 activation is defective in common variable immune deficiency.

Lee J et al. (2006) Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells.

Bhan U et al. (2007) TLR9 is required for protective innate immunity in Gram-negative bacterial pneumonia: role of dendritic cells.

Hoarau C et al. (2007) TLR9 activation induces normal neutrophil responses in a child with IRAK-4 deficiency: involvement of the direct PI3K pathway.

Asagiri M et al. (2008) Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis.

Samuelsson C et al. (2008) Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection.

Ito T et al. (2009) TLR9 regulates the mycobacteria-elicited pulmonary granulomatous immune response in mice through DC-derived Notch ligand delta-like 4.

Babiuk S et al. (2004) TLR9-/- and TLR9+/+ mice display similar immune responses to a DNA vaccine.

O'Neill SK et al. (2009) Endocytic sequestration of the B cell antigen receptor and toll-like receptor 9 in anergic cells.

Zhang Q et al. (2010) Circulating mitochondrial DAMPs cause inflammatory responses to injury.

Kubarenko AV et al. (2010) A naturally occurring variant in human TLR9, P99L, is associated with loss of CpG oligonucleotide responsiveness.

Park B et al. (2011) Granulin is a soluble cofactor for toll-like receptor 9 signaling.

Oka T et al. (2012) Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure.

Ohto U et al. (2015) Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9.

Xu L et al. (2019) TLR9 signaling in fibroblastic reticular cells regulates peritoneal immunity.

Sato A et al. (2006) Dual recognition of herpes simplex viruses by TLR2 and TLR9 in dendritic cells.

Du X et al. (2000) Three novel mammalian toll-like receptors: gene structure, expression, and evolution.

Chuang TH et al. (2000) Cloning and characterization of a sub-family of human toll-like receptors: hTLR7, hTLR8 and hTLR9.

Kadowaki N et al. (2001) Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens.

Yang K et al. (2005) Human TLR-7-, -8-, and -9-mediated induction of IFN-alpha/beta and -lambda Is IRAK-4 dependent and redundant for protective immunity to viruses.

Ewald SE et al. (2008) The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.

Guiducci C et al. (2010) TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus.

Baumann CL et al. (2010) CD14 is a coreceptor of Toll-like receptors 7 and 9.

Phelan JD et al. (2018) A multiprotein supercomplex controlling oncogenic signalling in lymphoma.

Hasan M et al. (2008) Defective Toll-like receptor 9-mediated cytokine production in B cells from Bruton's tyrosine kinase-deficient mice.

Sasai M et al. (2010) Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3.

Hemmi H et al. (2000) A Toll-like receptor recognizes bacterial DNA.

Verthelyi D et al. (2001) Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs.

Takeshita F et al. (2001) Cutting edge: Role of Toll-like receptor 9 in CpG DNA-induced activation of human cells.

Leadbetter EA et al. (2002) Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors.

Latz E et al. (2004) TLR9 signals after translocating from the ER to CpG DNA in the lysosome.

Takeshita F et al. (2004) Transcriptional regulation of the human TLR9 gene.