Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
The TLR10 gene encodes a receptor which is probably involved in innate immunity, but whose biological role has to be elucidated yet.
| Clinic | Method | Carrier testing |
| Turnaround | 5 days | |
| Specimen type | genomic DNA |
| Clinic | Method | Massive parallel sequencing |
| Turnaround | 25 days | |
| Specimen type | genomic DNA |
| Research | Method | Genomic sequencing of the entire coding region |
| Turnaround | 25 days | |
| Specimen type | genomic DNA |
| 1. |
Kadowaki N et al. (2001) Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. 
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| 2. |
Chuang T et al. (2001) Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells.
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| 3. |
Zhang D et al. (2004) A toll-like receptor that prevents infection by uropathogenic bacteria.
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| 4. |
Hasan U et al. (2005) Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88.
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| 5. |
Yarovinsky F et al. (2005) TLR11 activation of dendritic cells by a protozoan profilin-like protein.
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| 6. |
Mourits VP et al. (2020) The role of Toll-like receptor 10 in modulation of trained immunity.
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