Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
The APOBEC3D gene encodes a protein of the APOBEC family. Enzymes of this family are responsible for mRNA editing. They introduce base exchanges before the protein is translated, which plays an important role in defense of viral infections and lipid metabolism.
| Clinic | Method | Carrier testing |
| Turnaround | 5 days | |
| Specimen type | genomic DNA |
| Research | Method | Genomic sequencing of the entire coding region |
| Turnaround | 25 days | |
| Specimen type | genomic DNA |
Disorders of mRNA editing
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APOBEC1
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APOBEC2
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APOBEC3A
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APOBEC3B
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APOBEC3C
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APOBEC3D
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APOBEC3F
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APOBEC3G
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APOBEC3H
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APOBEC4
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| 1. |
Jarmuz A et al. (2002) An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22. 
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| 2. |
NCBI article NCBI 140564
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| 3. |
OMIM.ORG article Omim 609900
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| 4. |
Wikipedia article Wikipedia EN (APOBEC3D)
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