Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
Moldiag Diseases Genes Support Contact

leprosy_susceptibility_to_5

leprosy_susceptibility_to_5

Systematic

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leprosy_susceptibility_to
leprosy_susceptibility_to_5
TLR1

References:

1.

Taguchi T et al. (1996) Chromosomal localization of TIL, a gene encoding a protein related to the Drosophila transmembrane receptor Toll, to human chromosome 4p14.

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2.

Omueti KO et al. (2007) The polymorphism P315L of human toll-like receptor 1 impairs innate immune sensing of microbial cell wall components.

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3.

Johnson CM et al. (2007) Cutting edge: A common polymorphism impairs cell surface trafficking and functional responses of TLR1 but protects against leprosy.

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4.

Misch EA et al. (2008) Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction.

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5.

Schuring RP et al. (2009) Polymorphism N248S in the human Toll-like receptor 1 gene is related to leprosy and leprosy reactions.

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