Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
The TLR6 gene encodes a receptor of bacterial lipopeptides located outside the cell membrane. Genetic variants are suspected to modulate susceptibility to leprosy and other mycobacterial diseases.
| Clinic | Method | Carrier testing |
| Turnaround | 5 days | |
| Specimen type | genomic DNA |
| Clinic | Method | Massive parallel sequencing |
| Turnaround | 25 days | |
| Specimen type | genomic DNA |
| Research | Method | Genomic sequencing of the entire coding region |
| Turnaround | 25 days | |
| Specimen type | genomic DNA |
| 1. |
Kadowaki N et al. (2001) Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. 
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| 2. |
Hoebe K et al. (2005) CD36 is a sensor of diacylglycerides.
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| 3. |
Kim S et al. (2009) Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis.
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| 4. |
Takeuchi O et al. (1999) TLR6: A novel member of an expanding toll-like receptor family.
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